The personalized medicine and organization of geriatric care of population

Abstract


The article presents advisability of applying approaches of personalized medicine to solve problems of modern gerontology and geriatrics. The actuality of issue is conditioned by population aging due to rapid increasing of both percentage and absolute number of elderly people in total population of most countries. The ideology of personalized medicine or P4 medicine is targeted to developing individual preventive and therapeutic activities for specific personality. The fundamental basis of developing personalized medicine is ensured by biomarkers, specific for every patient and certain disease. The elderly people health is characterized by increased susceptibility to diseases, polymorbidity and heterogeneity in health status. The solution of actual problems in gerontology and geriatrics improvement of basic principles of health care is needed with an emphasis on prognostication, prevention and personalized approach applied to elderly patients with the purpose of ameliorating their quality of life. The development and promotion of complex inter-disciplinary programs of personalized treatment of elderly patients is required.

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About the authors

N. N. Belushkina

The Federal State Budget Educational Institution of Higher Education “The M. V. Lomonosov Moscow State University”; The Federal State Budget Institution of Science “The N. M. Emanuel Institute of Biochemical Physics” of the Russian Academy of Sciences

Email: belushkina@rambler.ru

A. S. Chemezov

The Federal State Budget Educational Institution of Higher Education “The M. V. Lomonosov Moscow State University”


M. A. Paltsev

The Federal State Budget Educational Institution of Higher Education “The M. V. Lomonosov Moscow State University”; The Federal State Budget Institution of Science “The N. M. Emanuel Institute of Biochemical Physics” of the Russian Academy of Sciences


References

  1. Walko C. M., McLeod H. L. Personalizing Medicine in Geriatric Oncology. J. Clin. Oncol. 2014;32(24):2581-6. doi: 10.1200/JCO.2014.55.9047
  2. Roger V. L. Epidemiology of heart failure. Circ. Res. 2013;113:646-59.
  3. Белушкина Н. Н., Чемезов А. С., Пальцев М. А. Персонализированная медицина: от идеи до внедрения в практическое здравоохранение. Молекулярная медицина. 2018;16(3):9-15. doi: 10.29296/24999490-2018-03-02.
  4. Hermansson J., Kahan T. Systematic review of validity assessments of framingham risk score results in health economic modelling of lipid-modifying therapies in Europe. Pharmaco Economics. 2018;36:205-13. doi: 10.1007/s40273-017-0578-1
  5. Wu I-C., Lin C-C., Chao A., Hsiung C. A. Emerging roles of frailty and inflammaging in risk assessment of age-related chronic diseases in older adults: the intersection between aging biology and personalized medicine. BioMedicine. 2015;5(1):1-10.
  6. McVeigh T. P., Kerin M. J. Clinical use of the Oncotype DX genomic test to guide treatment decisions for patients with invasive breast cancer. Breast Cancer - Targets and Therapy. 2017;9:393-400. doi: 10.2147/BCTT.S109847
  7. Lopez-Otin C., Blasco M. A., Partridge L., Errano M., Kroemer G. The hallmarks of aging. Cell. 2013;153:1194-217.

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