Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot71010.32687/0869-866X-2021-29-5-1220-1224Научная статьяThe impact of re-vaccination implementation on morbidity of mumps in the Kyrgyz RepublicNiiazalievaM. S.niyazalieva_mira@mail.ruIsakovaZh. T.-ToygombaevaV. S.-AldjambaevaI. Sh.-The I. K. Akhunbaev Kyrgyz State Medical Academy151020212951220122422102021Copyright © 2021,2021The article presents results of evaluation of long-term dynamics of morbidity of mumps in the Kyrgyz Republic (KR) in the pre-vaccination period, after the introduction of routine mass immunization in 1978 and in beginning of re-vaccination since 2015. The pronounced trend of increasing of morbidity was noted since 1970. In 1978, the morbidity increased up to 194 times as compared to 1948. The annual growth rate was made up to 7.7%. The application of vaccination significantly effected morbidity and prevalence of mumps in the Republic. In the long-term dynamics a pronounced trend of morbidity decreasing with annual decreasing rate of 7.5%.In 2015, re-vaccination of children of 6 years old was introduced in the Republic. This action resulted in morbidity decreasing during the next three years (2016, 2017 and 2018). However, in 2019, an outbreak of morbidity covering both children under 14 years and the adults was registered.The level of IgG to virus of mumps was determined by enzyme-linked immunosorbent assay using the test-system “VectoParotit-IgG” (by Vector BEST, Russia). The analysis of seroepidemiological study established the highest specific weight of seronegative individuals in the age group of 1-4 years (51.5%, 95% CI 42.9-60.1), and proportion of seropositive individuals falls on the age groups of 30 years and over (85, 4%), 10-14 years (62%), 5-9 years (61.5%), 15-19 years (60%).post-vaccination immunitypopulation immunitymumpsantibodiesserological monitoringпоствакцинальный иммунитетпопуляционный иммунитетэпидемический паротитантителасерологический мониторинг1.Таточенко В. К., Озерецкий Н. А. Иммунопрофилактика: справочник. М.: ПедиатрЪ; 2018.2.Юминова Н. В., Контарова Е. О., Балаев Н. В., Артюшенко С. В., Контаров Н. А., Россошанская Н. В. Вакцинопрофилактика кори, эпидемического паротита и краснухи: задачи, проблемы и реалии. Эпидемиология и вакцинопрофилактика. 2011;4(59):40-4.3.Короткова В. А., Хомичук Т. Ф. Серологический мониторинг состояния коллективного иммунитета к инфекциям, управляемым средствами специфической профилактики, среди населения приморского края. Здоровье. Медицинская экология. Наука. 2016;3(6):102-7.4.Инфекционный бюллетень. СЭСиЗН 1998-2020 гг. Режим доступа: https://dgsen.kg/category/deyatelnost/upravlenie-profilaktiki-infekcionnY/ezhemesYachnYj-bjulleten-sjesizn5.Джумалиев Н. Д., Дьяченко П. Н. Очерки и статистические данные распределения инфекционной заболеваемости в Киргизии за 60 лет. М.: Фрунзе; 1979. 313 с.6.Тойгомбаева В. С., Исаков Т. Б., Усубалиева Ж. M., Исакова Ж. Т. Паразитологическая служба Кыргызской Республики и эпидситуация по паразитарным заболеваниям. Здравоохранение Кыргызстана. 2018;(2):169-72.