Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot68910.32687/0869-866X-2021-29-5-1083-1089Научная статьяThe pandemic as antagonism of entropy and neg-entropy in human interaction with environmentGazniukL. M-LipichT. I.lipich@bsu.edu.ruTrishinaT. V.-MezinovV. O.-The Federal State Autonomous Educational Institution of Higher Education “The Belgorod State National University”151020212951083108922102021Copyright © 2021,2021The article considers issue of substantiation of the anti-systemic dimension of pandemic. The combination of biocenosis, anthropocenosis and technology within the framework of systematic approach is demonstrated. The outline of structural aspects of pandemic as negative medianess, catastrophic extreme situation and antagonism of entropy and neg-entropy is presented. The analysis of constitutive character and structural aspects of anti-systemic dimension of pandemic is proposed. On the examples of pandemics of cholera, SARS, Ebola fever the occurrence of pandemic as a result of human technogenic intervention in environment is demonstrated. The concept of pandemic as specific version of anti-system is proposed. It is concluded that pandemic is a system with negative level of systemacy, that, firstly, occurs as a result of direct or indirect interference of anthropocenosis in biocenosis, resulting in mutual antagonism. Secondly, it manifests itself as mass disease. Thirdly, it is targeted to annihilation of all discrete and rigid structures, open and closed systems of anthropocenosis and biocenosis. Fourthly, it is described through negative medianess, extreme catastrophic situation and antagonism of entropy and neg-entropy.pandemicentropy processchaossystem deathneg-entropyanti-systemmicrobiocenosistechnogenic interferenceenvironmentbiocenosisanthropocenosisпандемияэнтропийные процессыхаоссмерть системынегэнтропияантисистемамикробиоценозтехногенное вмешательствоокружающая средабиоценоз и антропоценоз1.Луканова В. В. Феномен пандемії з точки зору системного підходу: до постановки питання. Науково-теоретичний альманах Грані. 2018;21(7):70-6.2.Хайдеггер М. Бытие и время. Пер. с нем. В. Бибихина. М.: Ad Marginem; 1997. 451 с.3.Хайдеггер М. Вопрос о технике. Пер. с нем. В. Бибихина. М.: Республика; 1993. C. 221-37.4.Пригожин И. Порядок из хаоса: новый диалог человека с природой. Пер. с англ. Ю. Данилова. М.: Прогресс; 1986. 432 с.5.Кулик А. В. Эволюция философских стратегий взаимодействия с хаосом. Днепропетровск: ДНУ; 2015. 438 с.6.Малиновский А. А. Тектология. Теория систем. Теоретическая биология. М.: Эдиториал УРСС; 2000. 448 с.7.Уемов А. И. Системный подход и общая теория систем. М.: Мысль; 1978. 272 с.8.Fincher C. L., Thornhill R. The Parasite-Stress Theory of Values and Sociality. New York: Springer Science & Business Media; 2014. 449 p.9.Collier L., Oxford J. Human Virology. Oxford University Press; 2006. 310 p.10.Wolfe N. The Viral Storm: The Dawn of a New Pandemic Age. NYC: Times Books; 2011. 324 p.11.Шах С. Пандемия: Всемирная история смертельных вирусов. Пер. с англ. М. Десятова. М.: Альпина Диджитал; 2016. 208 с.