Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot55910.32687/0869-866X-2021-29-3-451-455Научная статьяThe contemporary world trends in epidemiology of gonococcal infection: The publications reviewUfimtsevaM. A.-VoroshilinaE. S.-KomarovA. A.komarov94-5@mail.ruGurkovskayaE. P.-BochkarevYu. M.-VishnevskayaI. F.-The Federal State Budget Educational Institution of Higher Education “The Ural State Medical University” of Minzdrav of Russia1512202129345145514072021Copyright © 2021,2021The gonorrhea is a sexually transmitted infection caused by Neisseria gonorrhoeae. N. gonorrhoeae being tropic to columnar epithelium, primarily infects mucosa of urogenital system, rectum, pharynx and conjunctiva. According the WHO, in 2016 about 87 million of new cases of gonorrhea were registered in the age group of 15-49 years old. The number of new gonorrhea cases increases steadily in many countries. The significant contribution into propagation of infection is made by males practicing sex with males, migrants, commercial sex workers, ethnic minorities. The undetected cervical gonococcus infection can result in such severe complications as inflammatory diseases of organs of small pelvis and infertility that directly impacts the reproductive losses of population. The anorectal and and pharyngeal gonorrhea very often takes asymptomatic course that complicates diagnostic and effects the statistical picture of morbidity. The apprehension of world trends in epidemiology of gonococcal infection can become a key point in implementation and development of national and international programs of prevention of propagation of this disease. The review of national and world publications concerning actual clinical epidemiological characteristics of gonococcus infection was implemented through such on-line search systems as PubMed, Google Scholar, BioMed Central (95 publications in total). The conclusions are made about steady increasing of morbidity due to propagation of infection in groups of risky sexual behavior, application of modern diagnostic means and patterns of clinical course of gonorrhea. The role of sexually transmitted infections in development of infertility, inflammatory diseases of organs of small pelvis, miscarriage and reproductive losses of poplation is marked.sexually transmitted infectiongonorrheaepidemiologyreproductive lossesasymptomatic infectioninfertilityreviewгонореяэпидемиологиярепродуктивные потерибессимптомная инфекциябесплодиеобзор литературы[Кубанова А. А., Мелехина Л. Е., Кубанов А. А. Основные задачи развития дерматовенерологической помощи населению Российской Федерации на период до 2024 года. Результаты деятельности медицинских организаций по оказанию дерматовенерологической помощи населению Российской Федерации в 2017 году. Вестник дерматологии и венерологии. 2018;94(5):9-25. doi: 10.25208/0042-4609-2018-94-5-9-25][Александрова Г. А., Мелехина Л. Е., Богданова Е. В. Ресурсы и деятельность медицинских организаций дерматовенерологического профиля. Заболеваемость инфекциями, передаваемыми половым путем, заразными кожными болезнями и заболеваниями кожи за 2017-2018 годы. М.: ФГБУ ЦНИИОИЗ; 2019. 208 с.][Centers for Disease Control and Prevention. Sexually Transmitted Disease Surveillance 2018. Atlanta: U. S. Department of Health and Human Services; 2019. Available at: https://www.cdc.gov/std/stats18/STDSurveillance2018-full-report.pdf (accessed 09.02.2020).][Stenger M., Pathela P., Anschuetz G. Increases in therate of Neisseria gonorrhoeae amonggay, bisexual and other men who have sex with men (MSM) - findings from the STD Surveillance Network 2010-2015. Sex. Transm. Dis. 2017;44(7):393-7. doi: 10.1097/OLQ.0000000000000623][Payne L., Lawrence D., Soni S., Llewellyn C., Dean G. Investigating factors for increased gonorrhoea reinfection in men who have sex with men attending a genitourinary clinic: a qualitative study. Int. J. STD AIDS. 2017 Aug;28(9):858-63. doi: 10.1177/0956462416677916][LeFevre M. L. USPSTF: screening for chlamydia and gonorrhea. Ann. Intern. Med. 2014;161:902-10. doi: 10.7326/M14-1981][Weston E. J., Kirkcaldy R. D., Stenger M., Llata E., Hoots B., Torrone E. A. Narrative Review: Assessment of Neisseria gonorrhoeae Infections Among Men Who Have Sex with Men in National and Sentinel Surveillance Systems in the United States. Sex. Transm. Dis. 2018;45(4):243-9. doi: 10.1097/OLQ.0000000000000740][Grey J. A., Bernstein K. T., Sullivan P. S. Estimating the population sizes of men who have sex with men in US states and counties using data from the American Community Survey. JMIR Pub. Health Surveill. 2016;2(1):14. doi: 10.2196/publichealth.5365][Kirkcaldy R. D., Weston E., Segurado A. C., Hughes G. Epidemiology of gonorrhoea: a global perspective. Sex. Health. 2019;16:401-11. doi: 10.1071/SH19061][European Centre for Disease Prevention and Control. Gonorrhoea. In: ECDC. Annual epidemiological report for 2017. Stockholm: ECDC; 2019.][European Centre for Disease Prevention and Control. Surveillance atlas of infectious diseases. Stockholm: ECDC; 2017. Available at: http://atlas.ecdc.europa.eu/public/index.aspx?Dataset=27&HealthTopic=21 (accessed 09.02.2020).][Kodner C. Sexually transmitted infections in men. Prim. Care. 2003 Mar;30(1):173-91. doi: 10.1016/S0095-4543(02)00073-8][European Centre for Disease Prevention and Control. Surveillance systems overview for 2017. Stockholm: ECDC; 2018. Available at: http://ecdc.europa.eu/publications-data/surveillance-systems-overview-2017 (accessed 09.02.2020).][Newman L. M., Dowell D., Bernstein K. A tale of two gonorrhea epidemics: results from the STD Surveillance Network (SSuN). Public Health Rep. 2012;127(3):282-92. doi: 10.1177/003335491212700308][Bolan G. A., Sparling P. F., Wasserheit J. N. The emerging threat of untreatable gonococcal infection. N. Engl. J. Med. 2012 Feb 9;366(6):485-7. doi: 10.1056/NEJMp1112456][Public Health Agency of Canada. Report On Sexually Transmitted Infections in Canada, 2017. Ottawa, ON: Public Health Agency of Canada; 2019. P. 43-5.][George C., Makoroka L., Rourke S. B., Adam B. D., Remis R. S., Husbands W. HIV testing by black MSM in Toronto: Identifying targets to improve testing. SAGE Open. 2014;4(2). doi: 10.1177/2158244014529776][Nelson L. E., Tharao W., Husbands W. The epidemiology of HIV and other sexually transmitted infections in African, Caribbean and Black men in Toronto, Canada. BMC Infect. Dis. 2019;294:19. doi: 10.1186/s12879-019-3925-3][Public Health Agency of Canada. Section 5-Management and Treatment of Specific Infections & Section 6 - Specific Populations - Men Who Have Sex with Men (MSM)/Women Who Have Sex with Women (WSW). Canadian Guidelines on Sexually Transmitted Infections. Ottawa, ON: Public Health Agency of Canada; 2010.][Fowler T., Caley M., Johal R. Previous history of gonococcal infection as a risk factor in patients presenting with gonorrhoea. Int. J. STD AIDS. 2010;21:277-8.][The Kirby Institute (2017a). HIV, viral hepatitis and sexually transmissible infections in Australia. Annual Surveillance Report 2017. Sydney: The Kirby Institute, UNSW; 2018.][Choudhri Y., Miller J., Sandhu J., Leon A., Aho J. Gonorrhea in Canada, 2010-2015. Can. Commun. Dis. Rep. 2018;44(2):37-42. doi: 10.14745/ccdr.v44i02a01][The Kirby Institute (2017b). Bloodborne viral and sexually transmissible infections in Aboriginal and Torres Strait Islander people: Annual surveillance report 2017. Sydney: The Kirby Institute; UNSW Australia; 2018.][Bergquist E. P., Trolard A., Kuhlmann A. S., Loux T., Liang S. Y., Stoner B. P., Reno H. Undertreatment of chlamydia and gonorrhea among pregnant women in the emergency department. Int. J. STD AIDS. 2019. doi: 10.1177/0956462419880379][Short V. L., Totten P. A., Ness R. B. Clinical presentation of Mycoplasma genitalium infection versus Neisseria gonorrhoeae infection among women with pelvic inflammatory disease. Clin. Infect. Dis. 2009;48:41-7. doi: 10.1086/594123][Maynard M., Nunez U. R., BS, Tao J., et al. 963. Extragenital Chlamydia and Gonorrhea Among Females Visiting an STD Clinic. Open Forum Infect. Dis. 2019;6(Suppl. 2):S29-S30. doi: 10.1093/ofid/ofz359.065][Hosenfeld C. B., Workowski K. A., Berman S. Repeat infection with chlamydia and gonorrhea among females: a systematic review of the literature. Sex. Transm. Dis. 2009;36:478-89. doi: 10.1097/OLQ.0b013e3181a2a933][Walker C. K., Sweet R. L. Gonorrhea infection in women: prevalence, effects, screening, and management. Int. J. Womens Health. 2011;3:197-206. doi: 10.2147/IJWH.S13427][United Nations General Assembly. Transforming our world: the 2030 Agenda for Sustainable Development, 2015. Available at: https://sustainabledevelopment.un.org/post2015/transformingourworld/publication (accessed 09.02.2020).][Global strategy for the prevention and control of sexually transmitted infections: 2006-2015. Available at: http://www.who.int/hiv/pub/toolkits/stis_strategy[1]en.pdf (accessed 09.02.2020).]