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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2610</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2026-34-2-285-290</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>THE FRACTAL CYBERNETIC ARCHITECTURE OF THE REGIONAL ANTI-NARCOTIC STRATEGY BASED ON MODEL ORIENTED SYSTEMIC ENGINEERING AS A TOOL OF INTERSECTORAL ADAPTIVE MANAGEMENT</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Akhokhova</surname><given-names>A. V.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Lyutsko</surname><given-names>V. V.</given-names></name><email></email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Tkhagapsoeva</surname><given-names>M. K.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zheligotova</surname><given-names>D. V.</given-names></name><email></email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff id="aff-1">The Federal State Budgetary Educational Institution of Higher Education "The Kabardino-Balkarian State University named after Kh. M. Berbekov, Ministry of Education and Science of the Russian Federation", 360004, Nalchik, Russia</aff><aff id="aff-2">The State Budgetary Institution "The Republican Clinical Center of Psychiatry and Narcology" of the Minzdrav of the Kabardino-Balkaria Republic, 360032, Nalchik, Russia</aff><aff id="aff-3">The Federal State Budgetary Institution "The Central Research Institute for Health Organization and Informatics" of the Minzdrav of Russia, 127254, Moscow, Russia</aff><aff id="aff-4">The Federal State Autonomous Educational Institution of Higher Education "The Patrice Lumumba Peoples' Friendship University of Russia" of the Minobrnauka of Russia (RUDN University), 117198, Moscow, Russia</aff><pub-date date-type="epub" iso-8601-date="2026-04-21" publication-format="electronic"><day>21</day><month>04</month><year>2026</year></pub-date><volume>34</volume><issue>2</issue><fpage>285</fpage><lpage>290</lpage><history><pub-date date-type="received" iso-8601-date="2026-04-22"><day>22</day><month>04</month><year>2026</year></pub-date></history><permissions><copyright-statement>Copyright © 2026,</copyright-statement><copyright-year>2026</copyright-year></permissions><abstract>This article substantiates the choice of fractal cybernetic architecture of regional anti-narcotic strategy based on the principles of the model-oriented systemic engineering. It is established that the tools of both traditional management by objectives and KPI-oriented management have predominantly reactive and fragmented patterns that reduces their efficiency in conditions of high dynamic of narcotics market and interdepartmental dissociation. The methodological basis was composed by the W. R. Ashbys Law of requisite variety and the S. Beers model of viable system that permitted to interpret the anti-narcotic strategy as adaptive multi-level social medical system. As a result, the executable fractal cybernetic model-based systems engineering architecture was formed that incorporated goal-setting, structural, modeling, digital, and measurement loops and ensured goal traceability, coordination of interdepartmental processes and closing feedback loops. On the basis of materials from the Kabardino-Balkarian Republic, the feasibility of the architecture through the digital platform AURA-FORECAST, integration of interdepartmental data and support of management decisions in the cycle of monitoring and adjustment is demonstrated. The obtained results form the evidence-based basis of transition from reactive anti-narcotic policy to predictive and adaptive model of management in health care.</abstract><kwd-group xml:lang="en"><kwd>Model-Based Systems Engineering</kwd><kwd>AURA-FORECAST</kwd><kwd>fractal cybernetic architecture</kwd><kwd>regional anti-narcotics strategy</kwd><kwd>model-based systems engineering</kwd><kwd>adaptive management</kwd><kwd>law of requisite variety</kwd><kwd>model of viable system</kwd><kwd>digital transformation of health care</kwd><kwd>predictive management</kwd><kwd>AURA-FORECAST</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>фрактально-кибернетическая архитектура</kwd><kwd>антинаркотическая стратегия региона</kwd><kwd>адаптивное управление</kwd><kwd>закон необходимого разнообразия</kwd><kwd>модель жизнеспособной системы, цифровая трансформация здравоохранения</kwd><kwd>предиктивное управление</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ashby W. 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