Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot246810.32687/0869-866X-2025-33-6-1317-1323Научная статьяTHE ETHICS OF BIOMEDICAL RESEARCH IN CONDITIONS OF DEVELOPMENT OF AI TECHNOLOGIESBryzgalinaE. V.ZudinA. B.The Federal State Budget Educational Institution of Higher Education The M. V. Lomonosov Moscow State University, 119991, Moscow, RussiaN. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russia151220253361317132319122025Copyright © 2025,2025Nowadays, AI technologies are an integral part of modern science. The processes of broad implementation of AI technologies into research activities became a challenge to ethical foundations of science functioning as social institution, capable not only to change established characteristics of research processes, but also to cause risks of wide propagation of academic fraud. The AI tools have a number of advantages determining scales increase and expansion of areas of their application in processes of receiving and presenting scientific results. The article outlines directions of AI application in research activities. The various positions regarding capabilities of AI technologies at different stages of scientific search. The key ethical risks and areas of ethical reflection on AI tools of scientific research in the field of bio-medicine are emphasized. The formats of putting and solving problems of ethics of science on external and internal contour, including consideration of specifics of biomedical research involving humans are analyzed. The tasks of reflection on processes of research transformation under AI influence and development of guidelines of proper application of AI technologies are substantiated. The tasks of maintaining quality of scientific research and compliance with established ethical standards of science are consideredsciencebiologymedicineAIethics of scienceacademic fraudнаукабиологиямедицинаискусственный интеллектэтика наукиакадемическое мошенничество[Национальная стратегия развития искусственного интеллекта на период до 2030 года, пункт 171. Режим доступа: http://www.kremlin.ru/acts/bank/44731/page/2 (дата обращения 10.06.2025).][Указ Президента Российской Федерации от 28 февраля 2024 г. №145 «О Стратегии научно-технологического развития Российской Федерации». Режим доступа: http://www.kremlin.ru/acts/bank/50358 (дата обращения 11.06.2025).][Указ Президента Российской Федерации от 10.10.2019 №490 «О развитии искусственного интеллекта в Российской Федерации» Режим доступа: http://www.kremlin.ru/acts/bank/44731 (дата обращения 11.06.2025).][Van Noorden R., Perkel J. M. AI and science: what 1,600 researchers think. Nature. 2023 Sep;621(7980):672—5. doi: 10.1038/d41586-023-02980-0][Researchers and AI. Survey Finding. Oxford University Press. 2024. Режим доступа: https://fdslive.oup.com/www.oup.com/academic/pdf/Researchers-and-AI-survey-findings.pdf (дата обращения 14.07.2025).][Брянцева О. В., Брянцев И. И. Проблема субъектности искусственного интеллекта в системе общественных отношений. Вестник ПАГС. 2023;3. Режим доступа: https://cyberleninka.ru/article/n/problema-subektnosti-iskusstvennogo-intellekta-v-sisteme-obschestvennyh-otnosheniy (дата обращения 11.07.2025).][Sayash Kapoor. REFORMS: Consensus-based Recommendations for Machine-learning-based Science. Sci. Adv. 2024;10:eadk3452. Режим доступа: https://www.science.org/doi/10.1126/sciadv.adk3452 (дата обращения 17.07.2025).][Broad W. How Hallucinatory A. I. Helps Science Dream Up Big Breakthroughs. The New York Times. Dec 23, 2024. Режим доступа: https://www.nytimes.com/2024/12/23/science/ai-hallucinations-science.html (дата обращения 17.07.2025).][Пресс-релиз. Режим доступа: https://www.nobelprize.org/prizes/chemistry/2024/press-release/ (дата обращения 10.07.2025).][Urbina F., Lentzos F., Invernizzi C. Dual use of artificial-intelligence-powered drug discovery. Nat. Mach. Intell. 2022;4:189—91.][The Empowering Role of Essay Writing Services: Nurturing Academic Excellence through Research Paper Writing Help. Режим доступа: https://ai4africa.org][Resnik D. B., Hosseini M. The ethics of using artificial intelligence in scientific research: new guidance needed for a new tool. AI Ethics. 2025;5:1499—521. doi: 10.1007/s43681-024-00493-8][Тищенко П. Д., Юдин Б. Г. Проблема добросовестности в научных исследованиях. Клиническая и экспериментальная хирургия. Журнал им. акад. Б. В. Петровского. 2013;(1):5—12.]