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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">2292</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2025-33-s1-884-888</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>DEVELOPMENT AND JUSTIFICATION OF THE EFFECTIVENESS OF A SET OF MEASURES AIMED AT EARLY DETECTION OF MALIGNANT NEOPLASMS</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Orlov</surname><given-names>A. E.</given-names></name><email></email></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zolotarev</surname><given-names>P. N.</given-names></name><email></email></contrib><contrib contrib-type="author"><name name-style="western"><surname>Somov</surname><given-names>A. N.</given-names></name><email></email></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zhdanov</surname><given-names>A. V.</given-names></name><email></email></contrib><contrib contrib-type="author"><name name-style="western"><surname>Frolov</surname><given-names>S. A.</given-names></name><email></email></contrib></contrib-group><pub-date date-type="epub" iso-8601-date="2025-08-31" publication-format="electronic"><day>31</day><month>08</month><year>2025</year></pub-date><volume>33</volume><fpage>884</fpage><lpage>888</lpage><history><pub-date date-type="received" iso-8601-date="2025-09-29"><day>29</day><month>09</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 1970,</copyright-statement><copyright-year>1970</copyright-year></permissions><abstract>The paper provides information on the development of a set of organizational measures. Activities involving the use of diagnostic and digital technologies. The events are aimed at early detection of colorectal cancer in the Samara region. The working group has developed an algorithm for colorectal cancer screening as part of a medical examination for the population aged 40 to 75 years. The algorithm determines the main tasks, the stage of screening, and the effectiveness criteria. The list of medical organizations that participated in the project has been determined. Work has been carried out on building tasks in the information system. Reporting forms have been developed for all project participants with a clear algorithm for filling them out, a single formation and direction of deadlines, and for all interested parties. The package of measures was issued in the form of orders from the Ministry of Health of the Samara region in 2023–2025. The complex of measures proved its effectiveness by increasing the number of newly diagnosed cases of colorectal cancer by 23%, as well as by reducing the proportion of patients with stage 3-4 colorectal cancer.</abstract><kwd-group xml:lang="en"><kwd>malignant neoplasms</kwd><kwd>colorectal cancer</kwd><kwd>population-based screening</kwd><kwd>set of measures</kwd><kwd>digital technologies</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>злокачественные новообразования</kwd><kwd>колоректальный рак</kwd><kwd>популяционный скрининг</kwd><kwd>комплекс мероприятий</kwd><kwd>цифровые технологии</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Bray F., Laversanne M., Sung H. et al. Global cancer statistics 2022: GLOBOCAN estimates of incidence and mortality worldwide for 36 cancers in 185 countries // CA: A Cancer Journal for Clinicians. 2024. Vol. 74, N 3. P. 229–263. 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