Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot213910.32687/0869-866X-2023-31-5-946-950Научная статьяTHE MOLECULAR GENETIC ASPECTS OF BASAL CELL CARCINOMA FROM THE POSITION OF POPULATION HEALTH PRESERVATIONKhabrievR. U.SadykovaR. N.MingazovaE. N.BespyatykhJ. A.2810202331594695005082025Copyright © 2023,2023The exploration of molecular genetic mechanisms that underlie carcinogenesis, hereditary factors of various oncological diseases, including basal cell carcinoma, the most common type of skin cancer is especially actual and significant for target strategies of public health. The diagnosis of basal cell carcinoma is based on complex clinical, radiologic and genetic examination data. The further research in the field of somatic or hereditary mutations in genes associated with basal cell carcinoma, including Patched 1 (PTCH1), Patched 2 (PTCH2), Smoothed (SMO) continue to be topical. The strategies of primary prevention of basal cell carcinoma, discussions of complex issues of decision making concerning treatment at primary health care level, training courses and development of guidelines for general practitioners and interdisciplinary recommendations for effective early diagnosis and comprehensive care of basal cell carcinoma are to be suggested.basal cell carcinomabasaliomaprevalencepopulationrisk factorsgenetic predispositionprimary health careмолекулярно генетические механизмыбазальноклеточная карцинома (базалиома)факторы наследственностипервичная медико санитарная помощьпервичная профилактика.Kavoussi H., Ebrahimi A., Rezaei M., Najafi F., Zarpoosh M., Kavoussi R. 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