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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">201</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2019-27-6-947-952</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>The trends of population general morbidity in the subjects of the Central Federal Okrug of the Russian Federation</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Starodubov</surname><given-names>V. I.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Leonov</surname><given-names>S. A.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Savina</surname><given-names>A. A.</given-names></name><bio></bio><email>a.savina@mednet.ru</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Feyginova</surname><given-names>S. I.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Alekseeva</surname><given-names>V. M.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zimina</surname><given-names>E. V.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-3"/></contrib></contrib-group><aff id="aff-1">The Federal State Budget Educational Institution of Higher Education “N. I. Pirogov Russian National Research Medical University” of Minzdrav of Russia</aff><aff id="aff-2">The Federal State Budget Institution “The Central Research Institute for Health Organization and Informatics” of Minzdrav of Russia</aff><aff id="aff-3">The State Budget Educational Institution of Higher Professional Education “The A. E. Evdokimov Moscow State University of Medicine and Dentistry” of Minzdrav of Russia</aff><pub-date date-type="epub" iso-8601-date="2019-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2019</year></pub-date><volume>27</volume><issue>6</issue><fpage>947</fpage><lpage>952</lpage><history><pub-date date-type="received" iso-8601-date="2021-04-06"><day>06</day><month>04</month><year>2021</year></pub-date></history><permissions><copyright-statement>Copyright © 2019,</copyright-statement><copyright-year>2019</copyright-year></permissions><abstract>The article presents the results of analysis of indices of total morbidity of population of the Central Federal Okrug (CFD) of the Russian Federation in 2010-2017. The significant differences in indices of total morbidity between the CFD subjects in certain ICD-10 classes were established. The indices of total morbidity of population during study period (8 years) in the Central Federal District factually didn't altered, while dynamics of indices in other subjects was characterized by multidirectionality. The gap in levels of total morbidity of population in the subjects was significant: from 115,123.6 per 100,000 of population in the Kursk Oblast to 194,404.1 per 100,000 of population in the Orel Oblast. The significant difference in rates of increase/ decrease of indices is noted. Thus, in Moscow decrease rate made up to 10%, while in the Orel Oblast morbidity increased up to 13.1%. Besides, in 2017, the Orel Region took a leadership in rate of increasing of total morbidity in such classes of diseases as infectious and parasitic diseases (39.3%), diseases of blood and blood-forming organs (49.1%), diseases of endocrine system (59,1%), diseases of nervous system (26.8%), diseases of respiratory system (28.2%), diseases of musculoskeletal system (16%), malformations (56%). It is very likely that this trend developed under influence of demographic situation in the subject due to significant increasing of percentage of people older than able-bodied age.The city of Moscow occupies leading position in decreasing of rate of prevalence of diseases and last but one place in level of total morbidity being inferior only to the Kursk Oblast. Thus, in Moscow was noted the most significant decreasing of morbidity in classes of infectious and parasitic diseases (26%) and diseases of digestive system (20.6%). The diseases of blood and blood-forming organs (235.2 per 100,000 population) and mental disorders (2353.5 per 100,000 population) were registered the less.The main contribution into trends of increasing or decreasing of indices is made by persons aged 18 years and older (74.1%).</abstract><kwd-group xml:lang="en"><kwd>prevalence</kwd><kwd>trends</kwd><kwd>the Central Federal District of the Russian Federation</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>показатели общей заболеваемости</kwd><kwd>темп прироста/убыли</kwd><kwd>Центральный федеральный округ Российской Федерации</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Демографический ежегодник России: Статистический сборник. М.: Росстат; 2017.</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Заболеваемость всего населения России в 2010 году. Статистический сборник. 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