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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1855</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2023-31-4-527-534</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>THE SOCIAL GENETIC ASPECTS OF HIGHER PREVALENCE AND PREVENTION OF BASAL CELL CARCINOMA</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Khabriev</surname><given-names>R. U.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Sadykova</surname><given-names>R. N.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Mingazova</surname><given-names>E. N.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-3"/><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Bespyatykh</surname><given-names>J. A.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-5"/></contrib></contrib-group><aff id="aff-1">N. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russia</aff><aff id="aff-2"></aff><aff id="aff-3">The Medical Biologic University of Innovations and Continuing Education of The Federal State Budget Institution “The A. I. Burnazyan State Scientific Center of The Russian Federation — Federal Medical Biophysical Center” of the Federal Medical Biological Agency of Russia, 123098, Moscow, Russia</aff><aff id="aff-4">The Federal State Budget Institution of Higher Education “The Kazan State Medical University” of Minzdrav of Russia, 420012, Kazan, Russia</aff><aff id="aff-5">The Federal State Budget Institution “The Academician Yu. M. Lopuhin Federal Scientific Clinical Center of Physicochemical Medicine” of the Federal Medical Biological Agency of Russia, 119435, Moscow, Russia</aff><pub-date date-type="epub" iso-8601-date="2023-08-25" publication-format="electronic"><day>25</day><month>08</month><year>2023</year></pub-date><volume>31</volume><issue>4</issue><fpage>527</fpage><lpage>534</lpage><history><pub-date date-type="received" iso-8601-date="2025-07-03"><day>03</day><month>07</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2023,</copyright-statement><copyright-year>2023</copyright-year></permissions><abstract>The article analyzes modern scientific publications that consider increasing of prevalence of basal cell carcinoma that ranks high among cases of skin cancer in all racial ethnic populations of the world, comparable with increasing prevalence of cancer of esophagus, ovaries and thyroid gland. In most countries of the world, including countries with high income level, reliable epidemiological data and national registers of basal cell carcinoma are absent. The multi-factorial etiology of basal cell carcinoma that includes environmental and genetic factors combined with social economic variables, is associated with prevalence of particular sub-types of basal cell carcinoma depending on gender, age, racial ethnic and genetic factors, as well as concomitant diseases, previous treatment and other indicators.</abstract><kwd-group xml:lang="en"><kwd>basal cell carcinoma</kwd><kwd>basalioma</kwd><kwd>prevalence</kwd><kwd>population</kwd><kwd>risk factor</kwd><kwd>genetic predisposition.</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>базальноклеточная карцинома</kwd><kwd>базалиома</kwd><kwd>распространенность</kwd><kwd>популяция</kwd><kwd>фактор риска</kwd><kwd>генетическая предрасположенность.</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>McDaniel B., Badri T., Steele R. B. Basal Cell Carcinoma. StatPearls [Internet]. 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