Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot179210.32687/0869-866X-2024-32-s2-1160-1164Научная статьяISSUES OF ROUTING PATIENTS WITH AUTOIMMUNE HEPATITISSalievK. G.SandlerYu. G.NikolskayaK. A.KhaimenovaT. Yu.KnyazevO. V.A. S. Loginov Moscow Clinical Research and Practical Center, 111123, Moscow, RussiaResearch Institute of Healthcare Organization and Medical Management of the Moscow Health Department, 115088, Moscow, RussiaRyzhikh National Medical Research Centre for Coloproctology, 123423, Moscow, Russia08112024321160116402072025Copyright © 1970,1970Autoimmune hepatitis is a chronic, immune-mediated liver disease characterized by an increased level of immunoglobulins G and/or gamma globulins, the presence of autoantibodies and a typical histological picture. Diagnosis of autoimmune hepatitis causes difficulties due to various variants of the course, wide variability of the clinical picture, which leads to a large number of missed cases of the disease. Treatment of аutoimmune hepatitis is aimed at reducing the activity of an inadequate response of the immune system against cells of its own body and achieving complete remission of the disease. The timeliness of starting treatment is directly related to the prognosis of the disease. These features of the disease necessitate proper patient routing and shortening their path to specialists with knowledge and experience in managing this category of patients.routing of patients with autoimmune hepatitisdiagnosis of autoimmune hepatitistreatment of autoimmune hepatitisаутоиммунный гепатитмаршрутизация пациентов с аутоиммунным гепатитомдиагностика аутоиммунного гепатиталечение аутоиммунного гепатитааutoimmune hepatitis[Lv T., Li M., Zeng N. et al. Systematic review and meta-analysis on the incidence and prevalence of autoimmune hepatitis in Asian, European, and American population // J. Gastroenterol. Hepatol. 2019. Vol. 34, N 10. P. 1676—1684. DOI: 10.1111/jgh.14746][Czaja A. J. Autoimmune hepatitis in diverse ethnic populations and geographical regions // Exp. Rev. Gastroenterol. Hepatol. 2013. Vol. 7, N 4. P. 365—385. DOI: 10.1586/egh.13.21][Rizvi S., Gawrieh S. Autoimmune hepatitis in the elderly: diagnosis and pharmacologic management // Drugs Aging. 2018. Vol. 35, N 7. P. 589—602. DOI: 10.1007/s40266-018-0556-0][Yang F., Wang Q., Bian Z. et al. Autoimmune hepatitis: East meets West // J. Gastroenterol. Hepatol. 2015. Vol. 30, N 8. P. 1230—1236. DOI: 10.1111/jgh.12952][Ивашкин В. Т., Буеверов А. О., Маевская М. В., Абдулганиева Д. И. Клинические рекомендации по диагностике и лечению аутоиммунного гепатита. Министерство здравоохранения Российской Федерации. М.; 2013.][Czaja A. J. Autoimmune hepatitis. Part A: pathogenesis // Exp. Rev. Gastroenterol. Hepatol. 2007. Vol. 1, N 1. P. 113—128. DOI: 10.1586/17474124.1.1.113][European Association for the Study of the Liver. EASL Clinical Practice Guidelines: Autoimmune hepatitis [published correction appears in J. Hepatol. 2015; 63(6):1543-4 // J. Hepatol. 2015. Vol. 63, N 4. P. 971—1004. DOI: 10.1016/j.jhep.2015.06.030][Mack C. L., Adams D., Assis D. N. et al. Diagnosis and management of autoimmune hepatitis in adults and children: 2019 practice guidance and guidelines from the American Association for the Study of Liver Diseases // Hepatology. 2020. Vol. 72, N 2. P. 671—722. DOI: 10.1002/hep.31065][Lohse A. W., Sebode M., Bhathal P. S. et al. Consensus recommendations for histological criteria of autoimmune hepatitis from the International AIH Pathology Group: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology: Results of a workshop on AIH histology hosted by the European Reference Network on Hepatological Diseases and the European Society of Pathology // Liver Int. 2022. Vol. 42, N 5. P. 1058—1069. DOI: 10.1111/liv.15217][Ratziu V., Samuel D., Sebagh M. et al. Long-term follow-up after liver transplantation for autoimmune hepatitis: evidence of recurrence of primary disease // J. Hepatol. 1999. Vol. 30, N 1. P. 131—141. DOI: 10.1016/s0168-8278(99)80017-8][Широкова Е. Н., Ивашкин К. В., Ивашкин В. Т. Аутоиммунный гепатит: новое в диагностике, патогенезе и лечении // Российский журнал гастроэнтерологии, гепатологии, колопроктологии. 2012. №5. С. 37—45.][Диагностика и лечение аутоиммунного гепатита в условиях стационарных и поликлинических учреждений: методические рекомендации / сост. Ю. Г. Сандлер, Е. В. Винницкая, Е. Н. Александрова и др. М.; 2022.]