Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot174910.32687/0869-866X-2024-32-s1-562-566Научная статьяTO ASSESS THE EFFECTIVENESS OF TREATMENT METHODS FOR PATIENTS OF DIFFERENT AGE GROUPS WITH BASAL CELL CANCER OF THE SKIN OF THE NOSE AND EARSVolginV. N.KagoianczR. V.SadykovaR. N.MingazovaE. N.Main Military Clinical Hospital named after Academician N. N. Burdenko, 105094, Moscow, RussiaClinical hospital «RZD-Medicine» of the city of Rostov-on-Don, 344011, Rostov-on-Don, RussiaN. A. Semashko National Research Institute of Public Health, 105064, Moscow, RussiaBiomedical University of Innovation and Continuing Education of the State Scientific Center of the Russian Federation — A. I. Burnazyan Federal Medical Biophysical Center of the Federal Medical Biological Agency of Russia, 123098, Moscow, RussiaTatarstan Аcademy of Sciences, 420111, Kazan, RussiaKazan State Medical University, 420012, Kazan, Russia0907202432756256602072025Copyright © 1970,1970The relevance of the problems of diagnosis and treatment of skin cancer is currently determined not only by the high incidence rate, but by the existing difficulties in differential diagnosis and treatment with traditional methods. For localizations of basal cell skin cancer (BCSC) that are “inconvenient” for treatment, such as the external auditory canal, auricle, and wing of the nose, treatment is associated with certain difficulties and the possible appearance of a cosmetic defect, therefore, when choosing a treatment method, the anatomical features of these organs are taken into account. It has been determined that the effectiveness of treatment for primary BCSC of the nose and auricles is higher than recurrent one, and among the various treatment methods, the most effective and radical is the surgical method. The immediate results of treatment of BCSC in the form of PR by surgical method were 86.7%, which is statistically significant compared with other types of treatment (p lt; 0.05). Long-term treatment results with the surgical method are also higher (77%) compared to other methods, which is also statistically significant (p lt; 0.05).skin cancerbasal cell carcinomacarcinomapopulationtreatment methodsрак кожибазальноклеточный раккарциномабазалиоманаселениеметоды лечения[Каприн А. Д., Старинский В. В., Петрова Г. В. Состояние онкологической помощи населению России в 2018 году. М.; 2019. 236 с.][Каприн А. Д., Старинский В. В., Петрова Г. В. Злокачественные новообразования в России в 2017 году (заболеваемость и смертность). М.; 2018. 250 с.][Каприн А. Д., Старинский В. В., Состояние онкологической помощи населению России в 2021 году. М.; 2022. 239 с.][Каприн А. Д., Старинский В. В., Петрова Г. В. Злокачественные новообразования в России в 2018 году (заболеваемость и смертность). М.; 2019. 250 с.][Roewert-Huber J., Lange-Asschenfeldt B., Stockfleth E., Kerl H. Epidemiology and aetiology of basal cell carcinoma // Br. J. Dermatol. 2007. Vol. 157, Suppl 2. P. 47–51. DOI: 10.1111/j.1365-2133.2007.08273.x][Tanese K. Diagnosis and management of basal cell carcinoma // Curr. Treat. Options Oncol. 2019. Vol. 20, N 2. P. 13. DOI: 10.1007/s11864-019-0610-0][Хабриев Р. У., Садыкова Р. Н., Мингазова Э. Н., Беспятых Ю. А. Молекулярно-генетические аспекты базальноклеточной карциномы с позиций здоровьесбережения населения // Проблемы социальной гигиены, здравоохранения и истории медицины. 2023. Т. 31, №5. С. 946–950. DOI: 10.32687/0869-866X-2023-31-5-946-950][Клинические рекомендации: базальноклеточный рак кожи. М.; 2020. 91 с.][Khan N. H., Mir M., Qian L. et al. Skin cancer biology and barriers to treatment: Recent applications of polymeric micro/nanostructures // J. Adv. Res. 2021. Vol. 36. P. 223–247. DOI: 10.1016/j.jare.2021.06.014][Lopez A. T., Carvajal R. D., Geskin L. Secondary prevention strategies for nonmelanoma skin cancer // Oncology. 2018. Vol. 32, N 4. P. 195–200.][Thomson J., Hogan S., Leonardi-Bee J. et al. Interventions for basal cell carcinoma of the skin // Cochrane Database Syst. Rev. 2020. Vol. 11, N 11. P. CD003412. DOI: 10.1002/14651858][Хабриев Р. У., Садыкова Р. Н., Мингазова Э. Н., Беспятых Ю. А. Социально-генетические аспекты высокой распространенности и профилактики базальноклеточной карциномы // Проблемы социальной гигиены, здравоохранения и истории медицины. 2023. Т. 31, №4. С. 527–534. DOI: 10.32687/0869-866X-2023-31-4-527-534][Dika E., Scarfì F., Ferracin M. et al. Basal cell carcinoma: a comprehensive review // Int. J. Mol. Sci. 2020. Vol. 21, N 15. P. 5572. DOI: 10.3390/ijms21155572][Heath M. S., Bar A. Basal cell carcinoma // Dermatol. Clin. 2023. Vol. 41, N 1. P. 13–21. DOI: 10.1016/j.det.2022.07.005][Basset-Seguin N., Herms F. Update in the management of basal cell carcinoma // Acta Derm. Venereol. 2020. Vol. 100, N 11. P. adv00140. DOI: 10.2340/00015555-3495]