Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot16710.32687/0869-866X-2019-27-si1-677-686Научная статьяMoscow program of early detection and treatment of prostate cancerPushkarD. Yu.-GovorovA. V.-VasilyevA. O.alexvasilyev@me.comKolontarevK. B.-PrilepskayaE. A.-KovylinaM. V.-SadchenkoA. V.-SidorenkovA. V.-S. I. Spasokokukotsky City Clinical HospitalA. I. Evdokimov Moscow State University of Medicine and Dentistry151220192767768606042021Copyright © 2019,2019The aim of this study is to improve the results of detection and treatment of patients with prostate cancer (PCa) in the Moscow. For this purpose, we performed our own clinical diagnostic, epidemiological, autopsy, experimental and comparative studies that emphasize the relevance of the stated subject in the study of the diagnosis and treatment of patients with PCa. Urology Department of A. I. Evdokimov Moscow State University of Medicine and Dentistry was at the forefront of the Men's Health program in Moscow and in early 2003 it was the first to have an office for early diagnosis of prostate diseases, as part of the Program. Over 20,000 patients were screened for PCa. For the first time in Russia, methods for the early detection of PCa were investigated on a cohort of Russian men using PCA3 and the Prostate Health Index. The role and significance of prostate saturation biopsy was examined. The investigation of aspects of the morphological assessment of prostate diseases formed the basis for the development of an electronic atlas of PCa images. A series of studies on various prostate visualization methods, including Histoscanning system and MRI, have been performed. A new minimally invasive method for the treatment of prostate cancer has been introduced - a robot-assisted radical prostatectomy and cryoablation. The concept of surgical treatment of localized forms of PCa has been developed and the factors predicting the success of treatment have been determined. This study is reflected in numerous publications both in Russia and abroad, in monographs and dissertations.prostate cancerearly diagnosisscreeningimagingtreatmentresulteffectivenessрак предстательной железыранняя диагностикаскринингвизуализациялечениерезультатэффективность1.Andriole G. L., Crawford E. D., Grubb III R. L., et al. Mortality results from a randomized prostate-cancer screening trial. N. Engl. J. Med. 2009;360:1310-9.2.Колонтарев К. Б., Говоров А. В., Осипова Т. А., Сидоренков А. В., Пушкарь Д. Ю. Значение показателя -2проПСА и индекса здоровья простаты для больных раком предстательной железы: обзор литературы и данные российского проспективного исследования. Урология. 2015;(1):49-53.3.Говоров А. В., Васильев А. О., Ширяев А. А., Сухих С. О., Сидоренков А. В., Пушкарев А. В., Цыганов Д. И., Пушкарь Д. Ю. 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Suppl. 2016;15:498.8.Govorov A. V., Vasyliev A. O., Prilepskaya E. A. Prospective comparison of random TRUS biopsy versus Prostate Histoscanning-guided and random biopsy versus MRI-guided and random biopsy: which technique is optimal for prostate cancer detection and its Grade group detection? Abstract book of annual congress AUA; 2018.9.Patel V. R., Coelho R. F., Rocco B. Pentafecta: A new concept for reporting outcomes of robot-assisted laparoscopic radical prostatectomy. Eur. Urol. 2011;59:702-7.10.Novara G. Systematic review and meta-analysis of perioperative outcomes and complications after robot-assisted radical prostatectomy. Eur. Urol. 2012;62:431-52.11.Tewari A. K., Srivastava A., Sooriakumaran P. Use of a novel absorbable barbed plastic surgical suture enables a “self-cinching” technique of vesicourethral anastomosis during robot- assisted prostatectomy and improves anastomotic times. J. Endourol. 2010;24:1645-50.12.Williams S. B., Lei Y., Nguyen P. L. Comparative effectiveness of cryotherapy vs brachytherapy for localized prostate cancer. BJU Int. 2012;110:92-8.13.Malcolm J. B., Fabrizio M. D., Barone B. B. Quality of life after open or robotic prostatectomy, cryoablation or brachytherapy for localized prostate cancer. J. Urol. 2010;183:1822-8.14.Zherdev A. A., Tsiganov D. I., Shakurov A. V., Pushkarev A. V., Burkov I. A., Vasilyev A. O., Sukhikh S. O. An experimental study of thermal characteristics of minimally invasive cryoprobes in different cooling modes. Biomed. Еngineer. 2018;3:1-5.