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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1662</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2023-31-2-223-226</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>THE PSYCHOLOGICAL FACTORS OF RENUNCIATION OF ANTITUMORAL THERAPY BY WOMEN WITH BREAST CANCER (INTERNATIONAL PUBLICATIONS REVIEW)</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Ponomareva</surname><given-names>I. V.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-3"/><xref ref-type="aff" rid="aff-4"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Tsiring</surname><given-names>D. A.</given-names></name><email></email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Pakhomova</surname><given-names>Ya. N.</given-names></name><email></email><xref ref-type="aff" rid="aff-3"/><xref ref-type="aff" rid="aff-2"/><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff id="aff-1">The Federal State Autonomous Educational Institution of Higher Education “The Tomsk National Research State University”, 634050, Tomsk, Russia</aff><aff id="aff-2"></aff><aff id="aff-3">The Ural Branch of the Federal State Budget Educational Institution of Higher Education “The Financial University under the Government of the Russian Federation”, 454084, Chelyabinsk, Russia</aff><aff id="aff-4">The Federal State Budget Educational Institution of Higher Education “The Chelyabinsk State University”, 454084, Chelyabinsk, Russia</aff><pub-date date-type="epub" iso-8601-date="2023-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2023</year></pub-date><volume>31</volume><issue>2</issue><fpage>223</fpage><lpage>226</lpage><history><pub-date date-type="received" iso-8601-date="2025-06-24"><day>24</day><month>06</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2023,</copyright-statement><copyright-year>2023</copyright-year></permissions><abstract>The article presents analytical review of studies considering problem of patient refusal from antitumoral treatment, in particular of women with breast cancer. The analysis of main results of empirical studies describes factors associated with patient refusal from treatment. Among factors affecting decision making related to patient voluntarily refuse of treatment are toxicity of treatment (nausea and vomiting), senile age, disease stage, availability and type of medical insurance, characteristics of family status. Besides objective factors, such subjective factors as beliefs, values of patients are described. The deficiency of research studies concerning psychological factors of patient refusal of antitumoral treatment is established. However, patient loyalty to antitumoral treatment plays decisive role in prognosis of survival and favorable course of disease. In connection with that, studies covering such areas as psychological characteristics of personality of patients refusing of antitumoral treatment, verification of psychological factors of this voluntary refusal are required in order to organize continuum of oncological care of patients, their psychological maintenance and increasing of commitment to treatment.</abstract><kwd-group xml:lang="en"><kwd>breast cancer</kwd><kwd>treatment refusal</kwd><kwd>treatment toxicity</kwd><kwd>quality of life</kwd><kwd>research review</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>рак молочной железы</kwd><kwd>отказ от лечения</kwd><kwd>токсичность лечения</kwd><kwd>качество жизни</kwd><kwd>обзор исследований</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Breast Source: Globocan 2020. Режим доступа: 20-Breast-fact-sheet.pdf</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Каприн А. Д., Старинский В. 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