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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1506</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2024-32-4-711-716</article-id><article-categories><subj-group subj-group-type="heading"><subject>Неопределен</subject></subj-group></article-categories><title-group><article-title>The factors determining motivation of blood plasma donorship, including conditions of COVID-19 pandemic</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Khokhriakov</surname><given-names>A L</given-names></name><email>hohryakov-al@rosplasma.ru</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Plutnicki</surname><given-names>A N</given-names></name><email>mbufmbc@mail.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Mingazova</surname><given-names>E N</given-names></name><email>elmira_mingazova@mail.ru</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-3"/><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff id="aff-1">The Medical Biological University of Innovations and Continuous Education of The Medical Biological University of Innovations and Post-Graduate Education of the Federal State Budget Institution “The A. I. Burnazyan State Research Center of the Russian Federation — Federal Medical Biophysical Center” of The Federal Medical Biological Agency of Russia, 123098, Moscow, Russia</aff><aff id="aff-2">The Federal State Budget Institution “The Russian Medical Scientific Practical Center “Rosplasma”” of the Federal Medical Biological Agency of Russia, 610002, Kirov, Russia</aff><aff id="aff-3">N. A. Semashko National Research Institute of Public Health, 105064, Moscow, Russia</aff><aff id="aff-4">The Federal State Budget Educational Institution of Higher Education “The Kazan State Medical University”, 420012, Kazan, Russia</aff><pub-date date-type="epub" iso-8601-date="2024-08-17" publication-format="electronic"><day>17</day><month>08</month><year>2024</year></pub-date><volume>32</volume><issue>4</issue><history><pub-date date-type="received" iso-8601-date="2025-04-23"><day>23</day><month>04</month><year>2025</year></pub-date><pub-date date-type="accepted" iso-8601-date="2025-04-23"><day>23</day><month>04</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025,</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>&lt;p&gt;The article analyzes publications considering motivation of plasma donors by factors related to ethical and socio-economic aspects. Their detailed analysis and systematical consideration in the work contributes into more effective informing of new potential donors, improving recruitment and retention of donors. The detailed analysis established among causes of negative beliefs and negative experiences regarding donorship such factors as increased risk of infectious diseases, decreased vitality, vaso-vagal reactions and reduced iron content. It is demonstrated that experienced plasma donors try to maintain practice of donorship in conditions of intensive life activity, often applying flexible approach to frequency of plasma donation. Their knowledge about contribution that their donation makes is key factor in continuing donation. However, the COVID-19 pandemic developed additional obstacles to donorship due to state preventive measures and increased personal health risks. In order to develop donorship policy during pandemic in the future, it is important to study changes in motivation of donors during pandemic.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>plasma donation</kwd><kwd>plasma donor</kwd><kwd>motivation</kwd><kwd>impact factor</kwd><kwd>COVID-19</kwd><kwd>pandemic</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>донорство плазмы</kwd><kwd>доноры плазмы</kwd><kwd>мотивация</kwd><kwd>факторы влияния</kwd><kwd>пандемия COVID-19</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Folléa G., Aranko K. European Blood Alliance. The revision of the European blood directives: A major challenge for transfusion medicine. Transfus. Clin. Biol. 2015;22(3):141–7. doi: 10.1016/j.tracli.2015.05.003</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Lemmens K. P., Abraham C., Ruiter R. A., Veldhuizen I. J., Dehing C. J., Bos A. E., Schaalma H. P. 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