<?xml version="1.0" encoding="UTF-8"?>
<!DOCTYPE root>
<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">149</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2019-27-si1-529-535</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>Deliberate medication poisoning in adolescence as a medical and socially significant problem</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Afukov</surname><given-names>I. I.</given-names></name><bio></bio><email>afukovdoc@yandex.ru</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Dolginov</surname><given-names>D. M.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Ipatova</surname><given-names>M. G.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kovalenko</surname><given-names>A. A.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Buromskaya</surname><given-names>N. I.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff id="aff-1">N. F. Filatov Children City Hospital No.13</aff><aff id="aff-2">N. I. Pirogov Russian National Research Medical University</aff><aff id="aff-3">Medical Academy of Continuing Professional Education</aff><aff id="aff-4">G. E. Sukhareva Scientific and Practical Center for Mental Health of Children and Adolescents</aff><pub-date date-type="epub" iso-8601-date="2019-12-15" publication-format="electronic"><day>15</day><month>12</month><year>2019</year></pub-date><volume>27</volume><fpage>529</fpage><lpage>535</lpage><history><pub-date date-type="received" iso-8601-date="2021-04-06"><day>06</day><month>04</month><year>2021</year></pub-date></history><permissions><copyright-statement>Copyright © 2019,</copyright-statement><copyright-year>2019</copyright-year></permissions><abstract>One of the urgent medical and social problems of modern society is the steady growth of auto-aggressive behavior and deliberate medication poisoning among adolescents and young adults. This investigation was held to optimize the provision of specialized medical care for acute deliberate self-poisoning in teenagers. We examined 498 patients admitted to the Toxicology Department of N. F. Filatov Children City Clinical Hospital No. 13 with a diagnosis of acute deliberate medication poisoning. The diagnosis was confirmed by chemical and toxicological urine test using thin-layer chromatography. From 2016 to 2018 the number of patients with deliberate medication poisoning increased by more than 2.5 times and amounted to 236 cases. Female patients were prevalent and accounted for up to 85% of cases. The leading position among medication self-poisoning is held by psychopharmacological drugs at 56%, in second place are non-steroidal anti-inflammatory drugs at 18.5%. The main causes of self-poisoning were social or family conflicts (47%), problems at school (35%), and Internet-related complaints (18%). The clinical manifestations of the disease in the acute period of chemical poisoning depended on the toxic agent and the dose taken. Psychological testing revealed a high level of neuroticism in 71% of adolescents, severe anxiety was observed in 57% of patients, and depression was diagnosed in 28% of cases. All patients were provided specialized medical care, including resuscitation, detoxification, and psychiatrist examination. Based on the accumulated clinical experience, an algorithm for managing adolescents with deliberate medication poisoning has been developed, which has reduced the number of repeated suicides by 1.8 times.</abstract><kwd-group xml:lang="en"><kwd>deliberate poisoning</kwd><kwd>medication</kwd><kwd>adolescents</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>преднамеренное отравление</kwd><kwd>лекарственные препараты</kwd><kwd>подростки</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Предотвращение самоубийств. Глобальный императив [Электронный ресурс]. Официальный сайт ВОЗ. Режим доступа: https://www.who.int/mental_health/suicide-prevention/world_report_2014/ru/</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Иванова А. Е., Сабгайда Т. П., Семенова В. Г., Антонова О. И., Никитина С. Ю., Евдокушкина Г. Н., Чернобавский М. В. Ситуация с суицидами в России и мире. В кн.: Смертность российских подростков от самоубийств. М.: ЮНИСЕФ; 2011. С. 8-18.</mixed-citation></ref><ref id="B3"><label>3.</label><mixed-citation>Каршибаева Г. А. Особенности суицидального поведения в подростковом возрасте. Молодой ученый. 2015;(7):663-5. Режим доступа: https://moluch.ru/archive/87/16634/</mixed-citation></ref><ref id="B4"><label>4.</label><mixed-citation>Райгородский Д. Я., редактор. Практическая психодиагностика. Методики и тесты. Учебное пособие. Самара: Бахрах-М; 2001. C. 169-71.</mixed-citation></ref><ref id="B5"><label>5.</label><mixed-citation>Smets E. M., Garssen B., Bonke B., De Haes J. C. The Multidimensional Fatigue Inventory (MFI) psychometric qualities of an instrument to assess fatigue. J. Psychosom. Res. 1995;39(3):315-25.</mixed-citation></ref><ref id="B6"><label>6.</label><mixed-citation>Bagshaw S. M., George C., Bellomo R. A comparison of the RIFLE and AKIN criteria for acute kidney injury in critically ill patients. Nephrol. Dial. Transplant. 2008;23:1569-74.</mixed-citation></ref></ref-list></back></article>
