Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot146710.32687/0869-866X-2024-32-2-286-290НеопределенThe Russian priority of development of intravenous anesthesia (Report I).KrylovaSvetlana Vrosnouskrylova@mail.ruKrylovNikolay Nnnkrylov01@yandex.ruKarpenkoIgor Vkarpenko.iv@bk.ruThe Humanitarian Institute of the Autonomous Non-Profit Educational Organization of Higher Education “The Russian New University”, 105005, Moscow, RussiaThe Institute of Social Sciences of the Federal State Autonomous Educational Institution of Higher Education “The I. M. Sechenov First Moscow State Medical University” of Minzdrav of Russia (Sechenov University), 119991, Moscow, Russia180420243222104202521042025Copyright © 2025,2025<p>The article analyses research activities of the discoverers of Russian narcosis from the Military Medical Academy of St. Petersburg: the head of the Department of Pharmacology N. P. Kravkov, the head of the Department of Hospital Surgery S. P. Fedorov and his resident A. P. Eremich. They for the first time in the world developed ideas of comprehensive experimental substantiation and then safe clinical administration of preparation hedonal to achieve stage of safe general anesthesia and implementation of long-term and traumatic operations. The scientific works of Russian discoverers indicated fundamentally new direction in formation of anesthesiology in the Russian Empire and in the world. A. P. Eremich at stage of preparatory tests, working out technique of intravenous infusion, determination of range of safe therapeutic doses and creation of special installation facilitating work with hedonal during operations of Professor S. P. Fedorov, can be recognized as the first Russian anesthesiologist and also as the first National resuscitator.</p>history of medicinegeneral intravenous anesthesiahedonalN. P. KravkovS. P. FedorovA. P. Eremichистория медициныобщая внутривенная анестезиягедоналН. П. КравковС. П. ФедоровА. П. Еремич1.Cotton F. J. Deaths from Anæsthesia: And Lessons to be Drawn from them. Ann. Surg. 1913;58(6 Suppl):934–8. doi: 10.1097/00000658-191312000-000262.Flemming A. L. A Review of Inquests concerning Deaths during Anæsthesia, 1910–1913. Proc. R. Soc. Med. 1914;7(Sect Anaesth):17–24.3.Honan W. F., Hassler J. W. Intravenous Anæsthesia. Ann. Surg. 1913;58(6 Suppl):900–16. doi: 10.1097/00000658-191312000-000234.Schmiedeberg O. Lieber die pharmakologischem Wirkungen und die therapeutische Anwendung einiger Carbaminsaure-Ester. 1885–1886. Arch. Exp. Pathol. Pharmakol. 1885;20:203–16.5.Dresser H. Ein neues Hypnotikum der Urethangruppe. München Med. Wochen.1900;40:1310.6.Current Medical Literature, 1900 — An Epitome Of Current Medical Literature. Brit. Med. J. 1900;1(2051):61–4.7.Fedorov S. P. In memory of N. P. Kravkov. Vrachebnaya gazeta. 1929;20:2478–80 (in Russian).8.Lampsakov S. P. About the effect of hedonal on the animal organism. Experimental research [O dejstvii gedonala (hedonal) na zhivotny`j organizm: E`ksperim. issled.]: Dis. doct. med. sci. From Farmakol. lab. of prof. N. P. Kravkov. St. Petersburg: Tip. Shtaba Otdel`n. korp. zhandarm; 1902. 76 p. (in Russian).9.Krawkow N. P. Die Wirkung von Hedonal auf den Körper von Tieren. Arch. f. Exp. Path. Pharm. (Leipz.). 1908;Suppl. Band:317.10.Kravkov N. P. About hedonal chloroform anesthesia. Russkii vrach. 1903;2:1697–700 (in Russian).11.Fedorov S. P. About combined hedonal-chloroform anesthesia. Med. obozr. 1904;8:457–61 (in Russian).12.Mints V. M. About hedonal-chloroform anesthesia [O gedonal-khloroformnom narkoze]. T-vo skoropech. A. A. Levenson, tsenz.; 1905. 9 p. (From mag. “Khirurgiya” 1905 № 96) (in Russian).13.Burkhardt L. Die intravenöse Narkose mit Aether und Chloroform. München Med. Wochen. 1909;2:2365–69.14.Kravkov N. P. About intravenous hedonal anesthesia. Russkii vrach. 1910;12:405–11 (in Russian).15.Eremich A. P. About general anesthesia with hedonal. Str. 62-63 In: IX S»ezd rossiiskikh khirurgov. Moscow, 19–23 Dec 1909. Moscow; 1910. 280 p.( in Russian).16.Eremich A. P. About intravenous hedonal anesthesia (Experimental and clinical study) [O vnutrivennom gedonalovom narkoze (E`ksperimental`noe i klinicheskoe issledovanie)]: Dis. Doct. Med. St. Petersburg; 1910. 127 p. (in Russian).17.Fedorov S. P. Intravenous anesthesia with hedonal. Zhurn. akusherstva i zhenskikh boleznei. 1910;(5–6):1173–80 (in Russian).18.Simpson J. Y. Discovery of a new anaesthetic agent, more effective than sulphuric ether. Lancet. 1847;2:549–51. doi: 10.1016/S0140-6736(00)63271-319.Jeremitsch A. P. Die intravenöse Hedonalnarkose. Deutsche Zeitschr Chirurg. 1911;108:551–63.20.Fedoroff S. P. Die intravenöse Narkose. Zentralb. Chir. 1910;9:119–21.21.Fedoroff S. P., Jeremitsch A. P. Über allgemeine Hedonalnarkose. Zentralbl. Chir. 1910;9:316–8.22.Sidorenko A. T. Zur Frag der intravenösen Hedonalnarkose. Zentralbl Chir. 1910;37:1219–21.23.Polenov A. L. About the use of intravenous regional anesthesia. Gazeta Vrach. 1910;17:1331–3 (in Russian).24.Lichkovskii L. A. About hedonal anesthesia. Russkii Vrach. 1910;(9):1447–9 (in Russian).25.Oppel' V. A. Intravenous anesthesia with hedonal. Izvestiya Imperatorskoi Voenno-Meditsinskoi Akademii. 1911;22:3–19 (in Russian).