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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1458</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2024-32-2-231-236</article-id><article-categories><subj-group subj-group-type="heading"><subject>Неопределен</subject></subj-group></article-categories><title-group><article-title>The analysis of main causes of increasing of cost of social aftermath of drug addiction in the region according to results of repeated evaluation</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Tsarev</surname><given-names>S A</given-names></name><email>tsasergey@yandex.ru</email><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Scvortsova</surname><given-names>E S</given-names></name><email>scvortsova@mednet.ru</email><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff id="aff-1">ФГБУ «Центральный научно-исследовательский институт организации и информатизации здравоохранения» Минздрава России, 127254, г. Москва</aff><aff id="aff-2">The Federal State Budget Institution “The Central Research Institute for Health Organization and Informatics of Minzdrav of Russia”, 127254, Moscow, Russia</aff><pub-date date-type="epub" iso-8601-date="2024-04-18" publication-format="electronic"><day>18</day><month>04</month><year>2024</year></pub-date><volume>32</volume><issue>2</issue><history><pub-date date-type="received" iso-8601-date="2025-04-21"><day>21</day><month>04</month><year>2025</year></pub-date><pub-date date-type="accepted" iso-8601-date="2025-04-21"><day>21</day><month>04</month><year>2025</year></pub-date></history><permissions><copyright-statement>Copyright © 2025,</copyright-statement><copyright-year>2025</copyright-year></permissions><abstract>&lt;p&gt;The article presents an attempt to evaluate what factors could contribute into significant changes of both amount and structure of social cost of drug consumption in the region. The analysis, based on preserved basic principles of assessment, was applied to processes that occurred in both state and non-state spheres. The purpose of the study was to analyze main causes of dynamics of social cost of drug consumption during re-assessment. Materials and methods. The social cost of drug consumption in the Samara Oblast was re-assessed in 20172020 (first assessment was implemented in 20072010). The main causes of increasing of social cost of drug consumption were analyzed on the basis of the study results. Results. In Samara Oblast, due to financial and structural changes in state and non-state spheres, occurred increasing of social cost of drug consumption from 18.0 billion to 25.4 billion rubles per year. At that, percentage of social cost of drug consumption in the gross domestic product decreased from 2.9% to 1.6%. In general structure of expenses greatest changes affected percentage of social aftermath of drug addiction (increase from 17.8% to 26.1%) and expenses of drug consumers (decrease from 69.7% to 62.3%).&lt;br /&gt;Conclusions. The increase of absolute values of financial expenditures of the Oblast related to drug consumption conditioned by financial and structural changes in society, is accompanied by decreasing of percentage of ocial cost of drug consumption in value of gross domestic product. The main cause of its dynamics is significant increasing of gross regional product.&lt;/p&gt;</abstract><kwd-group xml:lang="en"><kwd>social cost</kwd><kwd>drug addiction</kwd><kwd>expenses of society</kwd><kwd>assessment</kwd><kwd>value of social cost of drug consumption</kwd><kwd>dynamics</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>социальная стоимость наркомании</kwd><kwd>расходы общества</kwd><kwd>оценка величины социальной стоимости наркопотребления в динамике</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Ivanec N. N., Kuklin A. A., Koshkina E. A. Social cost of drug addiction in the Ural Federal District. Moscow — Yekaterinburg: Institute of Economics of the Ural Federal District of the Russian Academy of Sciences; 2005. 128 p. (in Russian).</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Barrio P., Reynolds J., García-Altés A., Gual A., Anderson P. 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