Проблемы социальной гигиены, здравоохранения и истории медицины

0869-866X2412-2106

Joint-Stock Company Chicot

1151

10.32687/0869-866X-2023-31-1-5-10

Научная статья

The effect of application of monitoring and training programs on quality of antimicrobial drugs use in high-risk departments

Mingazova

E. N.

elmira_mingazova@mail.ruImankulova

A. S.

-Djumalieva

G. A.

-Sulaimanova

15122023

311510

19022023

2023

The antibiotic resistance as a problem acquired character of pandemic. The WHO included it in top ten global health threats. In low-income countries, the main goal of the WHO global action plan is to control increase of antimicrobial resistance with purpose to improve quality of antibiotics application.This purpose of study was to evaluate effectiveness of integrated program of rational application of antimicrobial drugs to improve quality of medical care in multidisciplinary surgical hospital in the Kyrgyz Republic.The research comprised several stages including establishment of prevalence of infection associated with provision of medical care and implementation of training programs of rational use of antimicrobial drugs to improve quality of medical care.The implementation of comprehensive training and monitoring programs at hospital level made it possible to reduce total consumption of antimicrobial drugs in Defined Daily Doses per 100 Bed-Days (DDD/100BD) by 2.4 times, mainly due to third-generation cephalosporins, and aminoglycosides, macrolides. As a result, financial expenditures for drugs purchase decreased up to 2.7 times. The practical implementation of recommendations of perioperative antibiotic prevention permitted to increase consumption of cephalosporins of first generation. To develop and to implement training and monitoring programs an integrated approach is needed that, taking into account the specifics of particular medical organization and conditions of multidisciplinary interaction. Further research is needed to study application of rational practices of using antimicrobial drugs, preventing occurrence of HAI, controlling increase of antibiotic resistance.

antibioticsantimicrobialsantimicrobial resistancedrug resistancedrug consumptionhigh-risk departmentquality

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