Problems of Social Hygiene, Public Health and History of MedicineProblems of Social Hygiene, Public Health and History of Medicine0869-866X2412-2106Joint-Stock Company Chicot107810.32687/0869-866X-2022-30-s1-1162-1166Научная статьяCROHN'S DISEASE. TO THE 90th ANNIVERSARY OF THE DESCRIPTIONShkurkoT. V.shkurkotania@yandex.ruKagramanovaA. V.-KnyazevO. V.-National Medical Research Centre for Coloproctology named after A. N. RyzhikhResearch Institute for Healthcare Organization and Medical Management of Moscow Healthcare DepartmentMoscow Clinical Scientific Center named after A. S. Loginov1511202230s11162116617112022Copyright © 2022,2022The article describes the main achievements in the study of Crohn's disease, first described as a disease of the terminal ileum, affecting mainly young people, characterized by subacute or chronic necrotizing and scarring inflammation. In subsequent years, the inflammatory disease was also detected in other parts of the gastrointestinal tract. This disease affects the entire intestine and can involve every part of the gastrointestinal tract, from the mouth to the anus. The history of the study of Crohn's disease for 90 years has made it possible to delve deeply into the pathogenesis of inflammation, but has not yet come closer to revealing its etiology. Therefore, it is impossible to talk about the possibility of recovery from CD.Crohn's diseaseulcerative colitishistoryболезнь Кронаязвенный колитистория описания[Crohn B. B., Ginzburg L., Oppenheimer G. D. Regional ileitis // JAMA. 1932. Vol. 99. P. 1323-1328.][Harris F., Bell G., Brunn H. Chronic cicatrizing enteritis: regional ileitis (Crohn): a new surgical entity // Surg. Gynecol. Obstet. 1933. P. 937.][Colp R. A case of non-specific granuloma of the terminal ileum and cecum // Surg. Clin. North Am. 1934. Vol. 14. P. 443-449.][McCallum D., Gray W. Metastatic Crohn’s disease // Br. J. Dermatol. 1976. Vol. 95. P. 551-554.][Greenstein A. J., Janowitz H. D., Sachar D. B. The extra-intestinal complications of Crohn’s disease and ulcerative coilitis: A study of 700 patients // Medicine. 1976. Vol. 55. P. 401-412.][Schwartz S. I. Delving into a discovery [editorial] // Contemp. Surg. 1981. Vol. 18. P. 9.][Armitage G., Wilson M. Crohn’s disease: A survey of the literature and a report on 34 cases // Br. J. Surg. 1950. Vol. 38. P. 182-193.][Berg A. A. An operative procedure for right-sided ulcerative colitis // Ann. Surg. 1936. Vol. 104, N 6. P. 1019-1023. DOI: 10.1097/00000658-193612000-00008][Ginzburg L., Oppenheimer G. D. Non-specific granulomata of the intestines (inflammatory tumors and strictures of the intestines) // Ann. Surg. 1933. Vol. 98. P. 1046-1062.][Alexander-Williams J. Historical review // Allan R., Rhodes J. M., Hanauer S. B. et a1. (eds): Inflammatory Bowel Disease. London; 1996. P. 3-12.][Morgagni G. B. Seat and causes of diseases. Book 111, Letter XXXI, Article 2. N.Y.; 1960. Vol. 2. P. 64.][Combe C., Saunders W. A singular case of stricture and thickening of the ileum // Medical Transactions of the Royal College of Physicians London. 1813. Vol. 4. P. 16-21.][Fielding J. Crohn’s disease in London in the latter half of the nineteenth century // Ir. J. Med. Sci. 1984. Vol. 153, N 6. P. 214-220.][Dalziel T. K. Chronic interstitial enteritis // BMJ. 1913. Vol. 2. P. 106-107.][Lilienthal H. Extirpation of the entire colon, the upper portion of the sigmoid flexure, and four inches of the ileum for hyperplastic colitis // Ann. Surg. 1903. Vol. 37. P. 616-617.][Moschcowitz E., Wilensky A. Non-specific granulomata of the intestine // Am. J. Med. Sci. 1923. Vol. 166. P. 4-66.][Wilks S., Moxon W. Lectures on pathological anatomy. London; 1875.][Bargen J., Weber H. Regional migratory chronic ulcerative colitis // Surg. Gynecol. Obstet. 1930. Vol. 50. P. 964-972.][Crohn B., Rosenak B. A combined form of ileitis and colitis // JAMA. 1936. Vol. 106. P. l-7.][Wells C. Ulcerative colitis and Crohn’s disease // Ann. R. Surg. Engl. 1952. Vol. 11. P. 105-120.][Lockhart-Mummery H. E., Morson B. C. Crohn’s disease (regional enteritis) of the large intestine and its distinction from ulcerative colitis // Gut. 1960. Vol. 1. P. 87-105.][Wells C. Ulcerative colitis and Crohn’s disease // Ann. R. Surg. Engl. 1952. Vol. 11. P. 105-120.][Crohn B., Rosenberg H. The sigmoidoscopic picture of chronic ulcerative colitis (non-specific) // Am. J. Med. Sci. 1925. Vol. 170. P. 220-228.][Lewisohn R. Segmental enteritis // Surg. Gynecol. Obstet. 1938. Vol. 66. P. 215-222.][Otani S. Pathology of regional enteritis and regional enterocolitis //j. Mt. Sinai Hosp. N. Y. 1955. Vol. 22, N 3. P. 147-158.][Парфенов А. И. Болезнь Крона: к 80-летию описания // Терапевтический архив. 2013. Т. 85, № 8. С. 35-42.]