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<article xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" article-type="research-article" dtd-version="1.1d1" xml:lang="en"><front><journal-meta><journal-id journal-id-type="publisher">Problems of Social Hygiene, Public Health and History of Medicine</journal-id><journal-title-group><journal-title>Problems of Social Hygiene, Public Health and History of Medicine</journal-title></journal-title-group><issn publication-format="print">0869-866X</issn><issn publication-format="electronic">2412-2106</issn><publisher><publisher-name>Joint-Stock Company Chicot</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="publisher-id">1058</article-id><article-id pub-id-type="doi">10.32687/0869-866X-2022-30-s1-1044-1049</article-id><article-categories><subj-group subj-group-type="heading"><subject>Научная статья</subject></subj-group></article-categories><title-group><article-title>FEATURES OF THE USE OF ANTIBACTERIAL DRUGS IN PATIENTS WITH COVID-19</article-title></title-group><contrib-group><contrib contrib-type="author"><name name-style="western"><surname>Kryukov</surname><given-names>A. V.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Kuznetsova</surname><given-names>E. V.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Temirbulatov</surname><given-names>I. I.</given-names></name><bio></bio><email>emirbulatov.ilyas@gmail.com</email><xref ref-type="aff" rid="aff-1"/><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Vechorko</surname><given-names>V. I.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author"><name name-style="western"><surname>Zhuravleva</surname><given-names>M. V.</given-names></name><bio></bio><email>-</email><xref ref-type="aff" rid="aff-3"/><xref ref-type="aff" rid="aff-4"/></contrib></contrib-group><aff id="aff-1">Russian Medical Academy of Continuous Professional Education</aff><aff id="aff-2">Municipal Clinical Hospital No. 15 named after O. M. Filatov of Department of Health of Moscow</aff><aff id="aff-3">Research Institute for Healthcare Organization and Medical Management of Moscow Healthcare Department</aff><aff id="aff-4">I. M. Sechenov First Moscow State Medical University of the Ministry of Healthcare of the Russian Federation (Sechenov University)</aff><pub-date date-type="epub" iso-8601-date="2022-11-15" publication-format="electronic"><day>15</day><month>11</month><year>2022</year></pub-date><volume>30</volume><issue>s1</issue><fpage>1044</fpage><lpage>1049</lpage><history><pub-date date-type="received" iso-8601-date="2022-11-17"><day>17</day><month>11</month><year>2022</year></pub-date></history><permissions><copyright-statement>Copyright © 2022,</copyright-statement><copyright-year>2022</copyright-year></permissions><abstract>The review traces the evolution of the section on the use of antibacterial drugs in the temporary guidelines of the Ministry of Health for the treatment of a new coronavirus infection. Diagnostic approaches that play an important role in deciding on the need and duration of antibacterial therapy are presented. Routine use of fluoroquinolones should be restricted due to the adverse safety spectrum. According to existing data, the tactic of short courses of antibacterial therapy for community-acquired pneumonia are not inferior in effectiveness to longer courses. Unjustified prescribing of antibiotics increases the cost of medical care, promotes the selection of resistant pathogens and leads to adverse side effects. Timely updating of clinical recommendations, implementation of programs to control the appointment of antibacterial agents in medical organizations and strengthening the role of the clinical pharmacology service can reduce these adverse events</abstract><kwd-group xml:lang="en"><kwd>COVID-19</kwd><kwd>COVID-19</kwd><kwd>antibiotics</kwd><kwd>resistance</kwd><kwd>drug safety</kwd><kwd>adverse reactions</kwd></kwd-group><kwd-group xml:lang="ru"><kwd>антибиотики</kwd><kwd>резистентность</kwd><kwd>лекарственная безопасность</kwd><kwd>нежелательные реакции</kwd></kwd-group></article-meta></front><body></body><back><ref-list><ref id="B1"><label>1.</label><mixed-citation>Huttner B. D., Catho G., Pano-Pardo J. R. et al. COVID-19: don’t neglect antimicrobial stewardship principles! // Clin. Microbiol. Infect. 2020. Vol. 26, N 7. P. 808-810. DOI: 10.1016/j.cmi.2020.04.024</mixed-citation></ref><ref id="B2"><label>2.</label><mixed-citation>Lai J., Ma S., Wang Y. et al. 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